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Pediatr Clin North Am. 2011 Apr;58(2):407-26, x. doi: 10.1016/j.pcl.2011.02.005.

Milk and soy allergy.

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  • 1Division of Pediatric Allergy and Immunology, Department of Pediatrics, Jaffe Institute for Food Allergy, The Mount Sinai School of Medicine, Box 1198, One Gustave L. Levy Place, New York, NY 10029-6574, USA.


Cow's milk allergy (CMA) affects 2% to 3% of young children and presents with a wide range of IgE and non-IgE-mediated clinical syndromes, which have a significant economic and lifestyle effect. It is logical that a review of CMA would be linked to a review of soy allergy because soy formula is often an alternative source of nutrition for infants who do not tolerate cow's milk. This review examines the epidemiology, pathogenesis, clinical features, natural history, and diagnosis of cow's milk and soy allergy. Cross-reactivity and management of milk allergy are also discussed.

Copyright © 2011 Elsevier Inc. All rights reserved.

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