Arch Intern Med. 2011 Mar 28;171(6):557-8. doi: 10.1001/archinternmed.2011.33.

Age-based exclusions from cardiovascular clinical trials: implications for elderly individuals (and for all of us): comment on "the persistent exclusion of older patients from ongoing clinical trials regarding heart failure".

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Division of Geriatric Medicine, Department of Medicine, The Meyers Primary Care Institute, 630 Plantation St, Worcester, MA 01605, USA. jerry.gurwitz@umassmed.edu

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The persistent exclusion of older patients from ongoing clinical trials regarding heart failure. [Arch Intern Med. 2011]
The persistent exclusion of older patients from ongoing clinical trials regarding heart failure.Cherubini A, Oristrell J, Pla X, Ruggiero C, Ferretti R, Diestre G, Clarfield AM, Crome P, Hertogh C, Lesauskaite V, et al. Arch Intern Med. 2011 Mar 28; 171(6):550-6.

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The persistent exclusion of older patients from ongoing clinical trials regarding heart failure. [Arch Intern Med. 2011]
The persistent exclusion of older patients from ongoing clinical trials regarding heart failure.
Cherubini A, Oristrell J, Pla X, Ruggiero C, Ferretti R, Diestre G, Clarfield AM, Crome P, Hertogh C, Lesauskaite V, et al. Arch Intern Med. 2011 Mar 28; 171(6):550-6.
[The exclusion of older patients from clinical trials regarding heart failure. Causes and consequences]. [Recenti Prog Med. 2012]
[The exclusion of older patients from clinical trials regarding heart failure. Causes and consequences].
Cherubini A, Cerenzia A, Zengarini E. Recenti Prog Med. 2012 Mar; 103(3):103-8.
Most hospitalized older persons do not meet the enrollment criteria for clinical trials in heart failure. [Am Heart J. 2003]
Most hospitalized older persons do not meet the enrollment criteria for clinical trials in heart failure.
Masoudi FA, Havranek EP, Wolfe P, Gross CP, Rathore SS, Steiner JF, Ordin DL, Krumholz HM. Am Heart J. 2003 Aug; 146(2):250-7.
Review The causes and effects of socio-demographic exclusions from clinical trials. [Health Technol Assess. 2005]
Review The causes and effects of socio-demographic exclusions from clinical trials.
Bartlett C, Doyal L, Ebrahim S, Davey P, Bachmann M, Egger M, Dieppe P. Health Technol Assess. 2005 Oct; 9(38):iii-iv, ix-x, 1-152.
Review [The difficulties of translating into daily clinical practice the favorable results of clinical trials in chronic heart failure]. [Ann Ital Med Int. 2000]
Review [The difficulties of translating into daily clinical practice the favorable results of clinical trials in chronic heart failure].
Licata G. Ann Ital Med Int. 2000 Jan-Mar; 15(1):28-38.

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Age-based exclusions from cardiovascular clinical trials: implications for elder...
Age-based exclusions from cardiovascular clinical trials: implications for elderly individuals (and for all of us): comment on "the persistent exclusion of older patients from ongoing clinical trials regarding heart failure".
Arch Intern Med. 2011 Mar 28 ;171(6):557-8. doi: 10.1001/archinternmed.2011.33.

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