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Eur J Clin Nutr. 2011 Jul;65(7):791-9. doi: 10.1038/ejcn.2011.36. Epub 2011 Mar 23.

Raw and processed fruit and vegetable consumption and 10-year stroke incidence in a population-based cohort study in the Netherlands.

Author information

  • 1Division of Human Nutrition, Wageningen University, Wageningen, The Netherlands. Linda.oudegriep@wur.nl

Abstract

BACKGROUND/OBJECTIVES:

Prospective cohort studies have shown that high fruit and vegetable consumption is related to a lower risk of stroke. Whether food processing affects this association is unknown. We evaluated the associations of raw and processed fruit and vegetable consumption independently from each other with 10-year stroke incidence and stroke subtypes in a prospective population-based cohort study in the Netherlands.

SUBJECTS/METHODS:

We used data of 20 069 men and women aged 20-65 years and free of cardiovascular diseases at baseline who were enrolled from 1993 to 1997. Diet was assessed using a validated 178-item food frequency questionnaire. Hazard ratios (HRs) were calculated for total, ischemic and hemorrhagic stroke incidence using multivariable Cox proportional hazards models.

RESULTS:

During a mean follow-up time of 10.3 years, 233 incident stroke cases were documented. Total and processed fruit and vegetable intake were not related to incident stroke. Total stroke incidence was 30% lower for participants with a high intake of raw fruit and vegetables (Q4: >262 g/day; HR: 0.70; 95% confidence intervals (95% CIs): 0.47-1.03) compared with those with a low intake (Q1: ≤92 g/day) and the trend was borderline significant (P for trend=0.07). Raw vegetable intake was significantly inversely associated with ischemic stroke (>27 vs ≤27 g/day; HR: 0.50; 95% CI: 0.34-0.73), and raw fruit borderline significantly with hemorrhagic stroke (>120 vs ≤120 g/day; HR: 0.53; 95% CI: 0.28-1.01).

CONCLUSIONS:

High intake of raw fruit and vegetables may protect against stroke. No association was found between processed fruit and vegetable consumption and incident stroke.

PMID:
21427746
[PubMed - indexed for MEDLINE]
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