This Statistical Brief presents data from the Healthcare Cost and Utilization Project (HCUP) on hospital utilization by patients with diabetes in 2008. Characteristics of hospital stays are compared between patients with diabetes and patients without diabetes in terms of length of stay, average and total hospital costs, payer, and comorbidities. Hospitalization rates for patients with diabetes per 100,000 persons are examined by region and income quartile at the patient ZIP Code level. All differences between estimates noted in the text are statistically significant at the 0.05 level or better.