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J Affect Disord. 1990 May;19(1):23-9.

The genetics of six neurotic disorders: a twin study.

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  • 1Clinical Research Unit for Anxiety Disorders, University of New South Wales, St. Vincent's Hospital, Sydney, Australia.


Persons who had met criteria for specific anxiety or depressive neuroses during their lifetime were identified from a sample of 446 pairs of adult twins. Although there was a genetic contribution to neuroticism and to symptoms, there was no inheritance of specific disorders. This concurs with previous work in a sample from the same Australian Twin Registry and with those from a Norwegian sample. It is concluded that while there is a genetic contribution to the predisposing trait, and therefore to the intermittent appearance of symptoms, this contribution is obscured by the grouping of symptoms into diagnoses and by the help seeking which is a prerequisite to clinical diagnosis.

[PubMed - indexed for MEDLINE]
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