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J Acquir Immune Defic Syndr. 2010 Dec;55 Suppl 2:S122-7. doi: 10.1097/QAI.0b013e3181fbcb4c.

Chemoprophylaxis for HIV prevention: new opportunities and new questions.

Author information

  • 1Division of Infectious Diseases, Department of Medicine, and Department of Community Health, Alpert Medical School, Brown University, Miriam Hospital, Providence, RI 02906, USA. Kenneth_Mayer@brown.edu

Abstract

Growing data suggest that antiretrovirals can be used as an effective means of HIV prevention. This article reviews the current status and future clinical prospects of utilizing antiretroviral chemoprophylaxis before and after high-risk HIV exposure to prevent HIV transmission. The discussion about using antiretrovirals as a means of primary HIV prevention has moved to the forefront of public health discourse because of a growing evidence base, the increased tolerability of the medications, the decreased cost, the ever-expanding formulary, and the limitations of other approaches.

PMID:
21406981
[PubMed - indexed for MEDLINE]
PMCID:
PMC3075435
Free PMC Article

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