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    J Periodontol. 2011 Sep;82(9):1304-13. Epub 2011 Mar 15.

    Loss of alveolar bone due to periodontal disease exhibits a threshold on the association with coronary heart disease.

    Source

    Department of Epidemiology, Colorado School of Public Health, University of Colorado Denver, Aurora, CO, USA. amy.alman@ucdenver.edu

    Abstract

    BACKGROUND:

    A number of epidemiologic studies were published that looked at the association between coronary heart disease (CHD) and periodontal disease. However, debate exists about whether this association is a true relationship or simply an example of an uncontrolled confounder. This retrospective cohort study examines the relationship between periodontal disease and CHD.

    METHODS:

    Digital panoramic radiographs were used to assess alveolar bone loss (ABL) using a Schei ruler. Participants consisted of Veterans Administration (VA) patients who were eligible for dental benefits and had a digital panoramic radiograph taken at the VA Medical Center, Denver, Colorado. Information on CHD and other important clinical variables were obtained from electronic medical records.

    RESULTS:

    The examination of the relationship between ABL and CHD revealed a significant non-linear relationship with a threshold at ≈ 20% bone loss with a doubling of the probability ratios of CHD compared to those at 7.5% bone loss.

    CONCLUSIONS:

    To our knowledge, this is the first study to demonstrate a non-linear relationship between ABL and CHD. A significant positive association between ABL and CHD was found at even low levels of bone loss between 10% and 20%.

    PMID:
    21405935
    [PubMed - indexed for MEDLINE]

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