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Pediatrics. 2011 Apr;127(4):754-9. doi: 10.1542/peds.2010-1971. Epub 2011 Mar 14.

An infant with trisomy 18 and a ventricular septal defect.

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  • 1Department of Pediatrics, University of Montreal, Montreal, Quebec, Canada.


Decisions for critically ill infants with trisomy 18 raise thorny issues about values, futility, the burdens of treatment, cost-effectiveness, and justice. We presented the case of an infant with trisomy 18 to 2 neonatologists with experience in clinical ethics, Annie Janvier and Felix Okah, and to a parent, Barbara Farlow. They do not agree about the right thing to do.

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