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J Bacteriol. 2011 May;193(9):2353-4. doi: 10.1128/JB.00045-11. Epub 2011 Mar 11.

Genome sequences of two Staphylococcus aureus ovine strains that induce severe (strain O11) and mild (strain O46) mastitis.

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  • 1INRA, UMR1253 Science et Technologie du Lait et de l'Œuf, F-35042 Rennes, France.


Staphylococcus aureus is a major etiological agent of mastitis in ruminants. We report here the genome sequences of two ovine strains that were isolated from gangrenous (strain O11) and subclinical (strain O46) ewe mastitis. Both strains belong to the same clonal complex. Despite this close genotypic relationship, the two isolates were shown to reproducibly induce highly divergent types of infections, either severe (O11) or mild (O46) mastitis, in an experimental ewe model.

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