FEBS Lett. 1990 Mar 26;262(2):185-8.

A second consensus sequence of ATP-requiring proteins resides in the 21-kDa C-terminal segment of myosin subfragment 1.

Burke M, Rajasekharan KN, Maruta S, Ikebe M.

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Department of Biology, Case Western Reserve University, Cleveland OH 44106.

Abstract

Previous comparisons of sequence homologies of ATP-requiring enzymes have defined three consensus sequences which appear to be involved in the binding of the nucleotide. One of these was identified in the N-terminal 27-kDa segment of the myosin heavy chain but the other two sequences have not hitherto been located in myosin. The present paper proposes that one of these other two consensus sequences is in the 21-kDa C-terminal portion of S1 and that it may contribute to the ATP binding domain.

PMID:: 2139854; [PubMed - indexed for MEDLINE]

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