Biochem Biophys Res Commun. 1990 Apr 30;168(2):574-9.

A yeast protein, homologous to the proteolipid of the chromaffin granule proton-ATPase, is important for cell growth.

Apperson M, Jensen RE, Suda K, Witte C, Yaffe MP.

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Department of Biology, University of California, San Diego, La Jolla 92093.

Abstract

We have characterized a gene, PPA1, adjacent to the yeast MAS2 gene. DNA sequence analysis of PPA1 predicts a hydrophobic protein of 23 kDa. This protein is homologous to the proteolipid of the bovine chromaffin granule proton ATPase and to the proteolipid of the yeast vacuolar proton ATPase. Gene disruption experiments indicate that the PPA1 protein is essential for viability in three unrelated yeast strains and important for optimal growth in a fourth strain.

PMID:: 2139779; [PubMed - indexed for MEDLINE]

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GENBANK/M35294

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cDNA sequence encoding the 16-kDa proteolipid of chromaffin granules implies gene duplication in the evolution of H+-ATPases. [Proc Natl Acad Sci U S A. 1988]
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Cited by 4 PubMed Central articles

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A yeast protein, homologous to the proteolipid of the chromaffin granule proton-...
A yeast protein, homologous to the proteolipid of the chromaffin granule proton-ATPase, is important for cell growth.
Biochem Biophys Res Commun. 1990 Apr 30 ;168(2):574-9.

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A yeast protein, homologous to the proteolipid of the chromaffin granule proton-ATPase, is important for cell growth.

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