Multipotent adult progenitor cells

Best Pract Res Clin Haematol. 2011 Mar;24(1):3-11. doi: 10.1016/j.beha.2011.01.006. Epub 2011 Mar 4.

Abstract

We here discuss the potency and characteristics of various adult derived adherent stem cells with special focus on multipotent adult progenitor cells (MAPC) isolated first in 2002 in our lab. We describe the potency of MAPC, our current understanding in relationship with novel insights gained in epigenetic modifications that increase cellular potency, and their possible clinical applications.

Publication types

  • Review

MeSH terms

  • Adult Stem Cells / physiology*
  • Animals
  • Embryonic Stem Cells / physiology
  • Epigenomics
  • Humans
  • Mice
  • Multipotent Stem Cells / physiology*
  • Rats
  • Stem Cell Research / ethics
  • Trophoblasts / cytology