Ann Neurol. 2011 Feb;69(2):292-302. doi: 10.1002/ana.22366.

Diagnostic criteria for multiple sclerosis: 2010 revisions to the McDonald criteria.

Polman CH, Reingold SC, Banwell B, Clanet M, Cohen JA, Filippi M, Fujihara K, Havrdova E, Hutchinson M, Kappos L, Lublin FD, Montalban X, O'Connor P, Sandberg-Wollheim M, Thompson AJ, Waubant E, Weinshenker B, Wolinsky JS.

Source

Department of Neurology, Free University, Amsterdam, the Netherlands. ch.polman@vumc.nl

Abstract

New evidence and consensus has led to further revision of the McDonald Criteria for diagnosis of multiple sclerosis. The use of imaging for demonstration of dissemination of central nervous system lesions in space and time has been simplified, and in some circumstances dissemination in space and time can be established by a single scan. These revisions simplify the Criteria, preserve their diagnostic sensitivity and specificity, address their applicability across populations, and may allow earlier diagnosis and more uniform and widespread use.

Comment in

Revised McDonald criteria: the persisting importance of cerebrospinal fluid analysis. [Ann Neurol. 2011]
Revised McDonald criteria: the persisting importance of cerebrospinal fluid analysis.Tumani H, Deisenhammer F, Giovannoni G, Gold R, Hartung HP, Hemmer B, Hohlfeld R, Otto M, Stangel M, Wildemann B, et al. Ann Neurol. 2011 Sep; 70(3):520; author reply 521. Epub 2011 Jun 27.
2010 revisions to McDonald criteria for diagnosis of multiple sclerosis: impact of 3-Tesla magnetic resonance imaging. [Ann Neurol. 2011]
2010 revisions to McDonald criteria for diagnosis of multiple sclerosis: impact of 3-Tesla magnetic resonance imaging.Kilsdonk ID, Barkhof F, Wattjes MP. Ann Neurol. 2011 Jul; 70(1):182-3. Epub 2011 Jun 27.
Diagnostic criteria in multiple sclerosis: headed in the right direction but still a ways to go. [Ann Neurol. 2011]
Diagnostic criteria in multiple sclerosis: headed in the right direction but still a ways to go.Rudick RA. Ann Neurol. 2011 Feb; 69(2):234-6.
Cerebrospinal fluid analysis in the 2010 revised McDonald's multiple sclerosis diagnostic criteria. [Ann Neurol. 2011]
Cerebrospinal fluid analysis in the 2010 revised McDonald's multiple sclerosis diagnostic criteria.Galea I, Freedman MS, Thompson EJ. Ann Neurol. 2011 Jul; 70(1):183; author reply 183-4.
Multiple sclerosis II: new diagnostic criteria, association with smoking and effects of cannabis on cognitive function. [J Neurol. 2011]
Multiple sclerosis II: new diagnostic criteria, association with smoking and effects of cannabis on cognitive function.Strupp M. J Neurol. 2011 May; 258(5):954-7.

PMID:: 21387374; [PubMed - indexed for MEDLINE]
PMCID:: PMC3084507

Free PMC Article

Publication Types, MeSH Terms

Publication Types

Research Support, Non-U.S. Gov't

MeSH Terms

LinkOut - more resources

Full Text Sources

Other Literature Sources

Medical

Multiple Sclerosis - MedlinePlus Health Information

Miscellaneous

See the articles recommended by F1000Prime's Faculty of 5,000 renowned researchers and clinicians, assisted by 5,000 associates. - F1000

Supplemental Content

Save items

Click here to read article using PubReader

Related citations in PubMed

Review Diagnostic criteria for multiple sclerosis: 2005 revisions to the "McDonald Criteria". [Ann Neurol. 2005]
Review Diagnostic criteria for multiple sclerosis: 2005 revisions to the "McDonald Criteria".
Polman CH, Reingold SC, Edan G, Filippi M, Hartung HP, Kappos L, Lublin FD, Metz LM, McFarland HF, O'Connor PW, et al. Ann Neurol. 2005 Dec; 58(6):840-6.
[Diagnosis of multiple sclerosis--the 2010 revision of the McDonald criteria]. [Ugeskr Laeger. 2012]
[Diagnosis of multiple sclerosis--the 2010 revision of the McDonald criteria].
Mathiesen HK, Sørensen PS. Ugeskr Laeger. 2012 Mar 26; 174(13):862-5.
Evaluation of the 2010 McDonald multiple sclerosis criteria in children with a clinically isolated syndrome. [Mult Scler. 2012]
Evaluation of the 2010 McDonald multiple sclerosis criteria in children with a clinically isolated syndrome.
Kornek B, Schmitl B, Vass K, Zehetmayer S, Pritsch M, Penzien J, Karenfort M, Blaschek A, Seidl R, Prayer D, et al. Mult Scler. 2012 Dec; 18(12):1768-74. Epub 2012 Apr 23.
MS, MRI, and the 2010 McDonald criteria: a Canadian expert commentary. [Neurology. 2012]
MS, MRI, and the 2010 McDonald criteria: a Canadian expert commentary.
Selchen D, Bhan V, Blevins G, Devonshire V, Duquette P, Grand'Maison F, Kremenchutzky M, Lapierre Y, Li D, von Riedemann SJ, et al. Neurology. 2012 Dec 4; 79(23 Suppl 2):S1-15.
Review The role of MRI in the diagnosis of multiple sclerosis. [Adv Neurol. 2006]
Review The role of MRI in the diagnosis of multiple sclerosis.
Traboulsee AL, Li DK. Adv Neurol. 2006; 98:125-46.

See reviews... See all...

Cited by 58 PubMed Central articles

Demyelinating Disease following Anti-TNFa Treatment: A Causal or Coincidental Association? Report of Four Cases and Review of the Literature. [Case Rep Neurol Med. 2013]
Demyelinating Disease following Anti-TNFa Treatment: A Causal or Coincidental Association? Report of Four Cases and Review of the Literature.
Andreadou E, Kemanetzoglou E, Brokalaki Ch, Evangelopoulos ME, Kilidireas C, Rombos A, Stamboulis E. Case Rep Neurol Med. 2013; 2013:671935. Epub 2013 May 16.
Involvement of oxidative stress in occurrence of relapses in multiple sclerosis: the spectrum of oxidatively modified serum proteins detected by proteomics and redox proteomics analysis. [PLoS One. 2013]
Involvement of oxidative stress in occurrence of relapses in multiple sclerosis: the spectrum of oxidatively modified serum proteins detected by proteomics and redox proteomics analysis.
Fiorini A, Koudriavtseva T, Bucaj E, Coccia R, Foppoli C, Giorgi A, Schininà ME, Di Domenico F, De Marco F, Perluigi M. PLoS One. 2013; 8(6):e65184. Epub 2013 Jun 7.
Mood disorder as the presenting manifestation of demyelination. [Case Rep Neurol. 2013]
Mood disorder as the presenting manifestation of demyelination.
Tapos D, Sivaswamy L. Case Rep Neurol. 2013 May; 5(2):104-9. Epub 2013 May 3.

See all...

Related information

Related Citations
Calculated set of PubMed citations closely related to the selected article(s) retrieved using a word weight algorithm. Related articles are displayed in ranked order from most to least relevant, with the “linked from” citation displayed first.
MedGen (Bookshelf cited)
Related records in MedGen based on citations in GeneReviews and Medical Genetics Summaries
References for this PMC Article
Citation referenced in PubMed article. Only valid for PubMed citations that are also in PMC.
Free in PMC
Free full text articles in PMC
Cited in PMC
Full-text articles in the PubMed Central Database that cite the current articles.
Cited in Books
NCBI Bookshelf books that cite the current articles.

Recent activity

Clear Turn Off Turn On

Diagnostic criteria for multiple sclerosis: 2010 revisions to the McDonald crite...
Diagnostic criteria for multiple sclerosis: 2010 revisions to the McDonald criteria.
Ann Neurol. 2011 Feb ;69(2):292-302. doi: 10.1002/ana.22366.

PubMed

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

PubMed

Result Filters

Display Settings:

Send to: