Eur Arch Psychiatry Neurol Sci. 1990;239(4):218-20.

Thiamine tetraphydrofurfuryl disulfide in nutritional polyneuropathy.

Source

Department of Neurology, Airlangga University, Faculty of Medicine, Dr. Soetomo Hospital, Surabaya, Indonesia.

Abstract

An open trial with thiamine tetrahydrofurfuryl disulphide (TTFD) was carried out on 44 patients with nutritional polyneuropathy who were admitted to the Neurological Department, Dr. Soetomo Hospital, Surabaya, Indonesia, Thirty-four patients showed improvement of their motor functions (P less than 0.01) with slight restoration of sensory function and reflexes (P less than 0.1). Of the 18 patients who were re-examined electrophysiologically 3 months later, 6 showed remarkable improvements. No side-effects were observed during TTFD treatment. It seemed that nutritional polyneuropathy in our low socio-economic patients was mostly caused by thiamine deficiency.

PMID:: 2138545; [PubMed - indexed for MEDLINE]

LinkOut - more resources

Medical

Malnutrition - MedlinePlus Health Information

Supplemental Content

Save items

Related citations in PubMed

Treatment of autism spectrum children with thiamine tetrahydrofurfuryl disulfide: a pilot study. [Neuro Endocrinol Lett. 2002]
Treatment of autism spectrum children with thiamine tetrahydrofurfuryl disulfide: a pilot study.
Lonsdale D, Shamberger RJ, Audhya T. Neuro Endocrinol Lett. 2002 Aug; 23(4):303-8.
Postgastrectomy polyneuropathy with thiamine deficiency. [J Neurol Neurosurg Psychiatry....]
Postgastrectomy polyneuropathy with thiamine deficiency.
Koike H, Misu K, Hattori N, Ito S, Ichimura M, Ito H, Hirayama M, Nagamatsu M, Sasaki I, Sobue G. J Neurol Neurosurg Psychiatry. 2001 Sep; 71(3):357-62.
Reversible acute axonal polyneuropathy associated with Wernicke-Korsakoff syndrome: impaired physiological nerve conduction due to thiamine deficiency? [J Neurol Neurosurg Psychiatry....]
Reversible acute axonal polyneuropathy associated with Wernicke-Korsakoff syndrome: impaired physiological nerve conduction due to thiamine deficiency?
Ishibashi S, Yokota T, Shiojiri T, Matunaga T, Tanaka H, Nishina K, Hirota H, Inaba A, Yamada M, Kanda T, et al. J Neurol Neurosurg Psychiatry. 2003 May; 74(5):674-6.
Review Drug therapy for chronic idiopathic axonal polyneuropathy. [Cochrane Database Syst Rev. 2004]
Review Drug therapy for chronic idiopathic axonal polyneuropathy.
Vrancken AF, van Schaik IN, Hughes RA, Notermans NC. Cochrane Database Syst Rev. 2004; (2):CD003456.
Review Best evidence topic report. Oral or intravenous thiamine in the emergency department. [Emerg Med J. 2004]
Review Best evidence topic report. Oral or intravenous thiamine in the emergency department.
Jackson R, Teece S. Emerg Med J. 2004 Jul; 21(4):501-2.

See reviews... See all...

Cited by 2 PubMed Central articles

A review of the biochemistry, metabolism and clinical benefits of thiamin(e) and its derivatives. [Evid Based Complement Alternat...]
A review of the biochemistry, metabolism and clinical benefits of thiamin(e) and its derivatives.
Lonsdale D. Evid Based Complement Alternat Med. 2006 Mar; 3(1):49-59.
Review Impairment, disability, or handicap in peripheral neuropathy: analysis of the use of outcome measures in clinical trials in patients with peripheral neuropathies. [J Neurol Neurosurg Psychiatry....]
Review Impairment, disability, or handicap in peripheral neuropathy: analysis of the use of outcome measures in clinical trials in patients with peripheral neuropathies.
Molenaar DS, de Haan R, Vermeulen M. J Neurol Neurosurg Psychiatry. 1995 Aug; 59(2):165-9.

Related information

Related Citations
Calculated set of PubMed citations closely related to the selected article(s) retrieved using a word weight algorithm. Related articles are displayed in ranked order from most to least relevant, with the “linked from” citation displayed first.
Compound (MeSH Keyword)
PubChem chemical compound records that are classified under the same Medical Subject Headings (MeSH) controlled vocabulary as the current articles.
Substance (MeSH Keyword)
PubChem chemical substance (submitted) records that are classified under the same Medical Subject Headings (MeSH) controlled vocabulary as the current articles.
Cited in PMC
Full-text articles in the PubMed Central Database that cite the current articles.

Recent activity

Clear Turn Off Turn On

Thiamine tetraphydrofurfuryl disulfide in nutritional polyneuropathy.
Thiamine tetraphydrofurfuryl disulfide in nutritional polyneuropathy.
Eur Arch Psychiatry Neurol Sci. 1990 ;239(4):218-20.

PubMed
Vascular disrupting agent DMXAA enhances the antitumor effects generated by ther...
Vascular disrupting agent DMXAA enhances the antitumor effects generated by therapeutic HPV DNA vaccines.
J Biomed Sci. 2011 Mar 8 ;18:21.

PubMed
Validation of exposure assessment and assessment of recruitment methods for a pr...
Validation of exposure assessment and assessment of recruitment methods for a prospective cohort study of mobile phone users (COSMOS) in Finland: a pilot study.
Environ Health. 2011 Mar 8 ;10:14.

PubMed
Exceptional lability of a genomic complex in rice and its close relatives reveal...
Exceptional lability of a genomic complex in rice and its close relatives revealed by interspecific and intraspecific comparison and population analysis.
BMC Genomics. 2011 Mar 8 ;12:142.

PubMed
Recruitment of high risk women for HIV prevention trials: baseline HIV prevalenc...
Recruitment of high risk women for HIV prevention trials: baseline HIV prevalence and sexual behavior in the CAPRISA 004 tenofovir gel trial.
Trials. 2011 Mar 7 ;12:67.

PubMed

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

PubMed

Result Filters

Display Settings:

Send to:

Thiamine tetraphydrofurfuryl disulfide in nutritional polyneuropathy.

Source

Abstract

Publication Types, MeSH Terms, Substances

Publication Types

MeSH Terms

Substances

LinkOut - more resources

Medical

Supplemental Content

Save items

Related citations in PubMed

Cited by 2 PubMed Central articles

Related information

Recent activity

Simple NCBI Directory

Getting Started

Resources

Popular

Featured

NCBI Information