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Exerc Sport Sci Rev. 2011 Jul;39(3):128-32. doi: 10.1097/JES.0b013e3182141f80.

Mitochondrial protection by resveratrol.

Author information

  • 1Reynolds Oklahoma Center on Aging, Departments of Geriatric Medicine and Physiology, University of Oklahoma Health Sciences Center, Oklahoma City, USA. zoltan-ungvari@ouhsc.edu

Abstract

Mitochondrial dysfunction and oxidative stress are thought to play important roles in mammalian aging. Resveratrol is a plant-derived polyphenol that exerts diverse antiaging activities, mimicking some of the molecular and functional effects of dietary restriction. This review focuses on the molecular mechanisms underlying the mitochondrial protective effects of resveratrol, which could be exploited for the prevention or amelioration of age-related diseases in the elderly.

PMID:
21383627
[PubMed - indexed for MEDLINE]
PMCID:
PMC3123408
Free PMC Article

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