Format

Send to:

Choose Destination
See comment in PubMed Commons below
Nat Methods. 2011 Apr;8(4):315-7. doi: 10.1038/nmeth.1580. Epub 2011 Mar 6.

A bioinformatic assay for pluripotency in human cells.

Author information

  • 1Zentrum für Integrative Psychiatrie, Kiel, Germany. fj.mueller@zip-kiel.de

Abstract

Pluripotent stem cells (PSCs) are defined by their potential to generate all cell types of an organism. The standard assay for pluripotency of mouse PSCs is cell transmission through the germline, but for human PSCs researchers depend on indirect methods such as differentiation into teratomas in immunodeficient mice. Here we report PluriTest, a robust open-access bioinformatic assay of pluripotency in human cells based on their gene expression profiles.

Comment in

PMID:
21378979
[PubMed - indexed for MEDLINE]
PMCID:
PMC3265323
Free PMC Article
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Nature Publishing Group Icon for PubMed Central
    Loading ...
    Write to the Help Desk