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Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 2011 Feb;33(1):22-4. doi: 10.3881/j.issn.1000-503X.2011.01.006.

Advances in insulin like growth factor binding protein 1 in the prognosis of acute myocardial infarction.

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  • 1Key Laboratory of Endocrinology of Ministry of Health, Department of Endocrinology,PUMC Hospital, CAMS and PUMC, Beijing 100730, China.


Insulin-like growth factor (IGF) is closely associated with cardiovascular diseases. Low IGF-I level and high insulin-like growth factor binding protein-1 (IGFBP-1) level in serum can be used as a marker in predicting the long term morbidity and mortality of acute myocardial infarction (AMI). The article reviews the recent advances in IGFBP-1 in the prognosis of AMI.

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