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Methods Mol Biol. 2011;719:415-33. doi: 10.1007/978-1-61779-027-0_19.

Integrating Omics data for signaling pathways, interactome reconstruction, and functional analysis.

Author information

  • 1'L Galvani' Interdept Center, University of Bologna, Bologna, Italy. p.tieri@unibo.it

Abstract

Omics data and computational approaches are today providing a key to disentangle the complex architecture of living systems. The integration and analysis of data of different nature allows to extract meaningful representations of signaling pathways and protein interactions networks, helpful in achieving an increased understanding of such intricate biochemical processes. We here describe a general workflow and relative hurdles in integrating online Omics data and analyzing reconstructed representations by using the available computational platforms.

PMID:
21370095
[PubMed - indexed for MEDLINE]
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