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Ophthalmic Surg Lasers Imaging. 2011 Jul-Aug;42(4):346-9. doi: 10.3928/15428877-20110210-02. Epub 2011 Feb 17.

Povidone-iodine before lidocaine gel anesthesia achieves surface antisepsis.

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  • 1Department of Ophthalmology, California Pacific Medical Center, San Francisco, CA 94115, USA.

Abstract

BACKGROUND AND OBJECTIVE:

Viscous lidocaine interferes with ocular surface antisepsis. The current study was designed to evaluate the impact on surface antisepsis of different application sequences with lidocaine gel and povidone-iodine solution.

MATERIALS AND METHODS:

Blood agar plates inoculated with Staphylococcus epidermidis were treated with varying sequences of 2% lidocaine gel and 5% povidone-iodine solution. The plates were then incubated at 37°C for 24 hours and bacterial growth was determined.

RESULTS:

Plates on which povidone-iodine was applied alone or prior to lidocaine gel demonstrated no bacterial growth regardless of whether the antiseptic was retained on the plate for 5 seconds or for 30 seconds. There was no statistically significant difference between bacterial growth on plates not treated with povidone-iodine and on plates treated with lidocaine gel alone or prior to povidone-iodine (P = .553 and P = .485, respectively).

CONCLUSION:

Povidone-iodine effectively reduces bacterial counts when applied alone or prior to lidocaine gel. Lidocaine gel was confirmed to be a barrier to antisepsis when administered prior to povidone-iodine.

Copyright 2011, SLACK Incorporated.

PMID:
21366185
[PubMed - indexed for MEDLINE]
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