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Nat Neurosci. 2011 Apr;14(4):426-7. doi: 10.1038/nn.2761. Epub 2011 Feb 27.

Self-related neural response to tailored smoking-cessation messages predicts quitting.

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  • 1Health Behavior and Health Education, University of Michigan, Ann Arbor, Michigan, USA. hchua@umich.edu


Tailored health interventions can be more effective in eliciting positive behavior change than generic interventions, but the underlying neural mechanisms are not yet understood. Here, 91 smokers participated in a functional magnetic resonance imaging session and a tailored smoking-cessation program. We found that increases in activation in self-related processing regions, particularly dorsomedial prefrontal cortex, to tailored messages predicted quitting during a 4-month follow-up.

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