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Genome Biol. 2011;12(2):217. doi: 10.1186/gb-2011-12-2-217. Epub 2011 Feb 24.

The properties and applications of single-molecule DNA sequencing.

Author information

  • 1Helicos BioSciences Corporation, Building 200LL, One Kendall Square, Cambridge, MA 02139, USA. jthompson@helicosbio.com

Abstract

Single-molecule sequencing enables DNA or RNA to be sequenced directly from biological samples, making it well-suited for diagnostic and clinical applications. Here we review the properties and applications of this rapidly evolving and promising technology.

PMID:
21349208
[PubMed - indexed for MEDLINE]
PMCID:
PMC3188791
Free PMC Article

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