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EBV-induced oncogenesis.

Authors

Raab-Traub N.

Source

Human Herpesviruses: Biology, Therapy, and Immunoprophylaxis. Cambridge: Cambridge University Press; 2007. Chapter 55.

Excerpt

The Epstein–Barr virus (EBV) is a human herpesvirus that is a ubiquitous infectious agent, infecting greater than 90% of the world’s population (Henle et al., 1969). The majority of infections occur early in life without significant illness. However, EBV is clearly an important factor in multiple human cancers. This dichotomy raises the question as to what are the unique aspects of infection in those who develop cancers. The study of EBV and its associated tumors points to specific interactions between environmental, genetic, and viral factors.

Copyright © Cambridge University Press 2007

PMID:
21348113
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