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J ECT. 2011 Mar;27(1):73-6. doi: 10.1097/YCT.0b013e3181da846a.

How is electrocardiogram influenced by electroconvulsive therapy in males and females?

Author information

  • 1Department of Anesthesiology and Reanimation, Gaziantep University School of Medicine, Gaziantep, Turkey. aysemizrak@mynet.com

Abstract

OBJECTIVES:

We aimed to investigate and compare the P duration and P dispersion (Pd) between male and female patients with a primary diagnosis of chronic schizophrenia disorder before and after the electroconvulsive therapy (ECT) period.

METHODS:

We obtained electrocardiograms of 50 healthy young volunteers which included 25 female (group F, n = 25) and 25 male patients (group M, n = 25). We measured minimum and maximum P wave durations (Pmin, Pmax) and Pd in milliseconds. Electrocardiography was performed before electroconvulsive therapy (ECT) and immediately after the ECT period after awakening. A 12-lead surface electrocardiogram was obtained from each subject in the supine position.

RESULTS:

The post-ECT P duration was significantly longer than the pre-ECT P duration in groups F and M (P = 0.01 and P = 0.008, respectively). The post-ECT Pd was significantly longer than the pre-ECT Pd in groups F and M (P = 0.0001 in both groups). A higher correlation (r) in group M was observed between the pre-ECT Pd and post-ECT P duration than in group F (r = 0.538, P = 006 in group M; r = 0.349, P = 08 in group F). There was no significant difference between the groups regarding hemodynamics.

CONCLUSIONS:

Electroconvulsive therapy in both sexes may influence atrial conduction as evidenced by the significantly prolonged Pmax and Pd in patients with a primary diagnosis of schizophrenia disorder.

PMID:
21343714
[PubMed - indexed for MEDLINE]
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