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Fitoterapia. 2011 Jun;82(4):676-81. doi: 10.1016/j.fitote.2011.02.006. Epub 2011 Feb 19.

Malaysianol A, a new trimer resveratrol oligomer from the stem bark of Dryobalanops aromatica.

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  • 1Faculty of Applied Sciences, Universiti Teknologi MARA, 40450 Shah Alam, Selangor Darul Ehsan, Malaysia.

Abstract

A new resveratrol trimer, malaysianol A (1), five known resveratrol oligomers: laevifonol (2), ampelopsin E (3), α-viniferin (4), ε-viniferin (5), diptoindonesin A (6), and bergenin (7) have been isolated from the acetone extract of the stem bark of Dryobalanops aromatica by combination of vacuum and radial chromatography techniques. Their structures were established on the basis of their spectroscopic evidence and comparison with the published data. The cytotoxic activity of the compounds was tested against several cell lines in which compound 4 was found to inhibit strongly the growth of HL-60 cell line.

Copyright © 2011 Elsevier B.V. All rights reserved.

PMID:
21338657
[PubMed - indexed for MEDLINE]
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