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Obes Surg. 2011 May;21(5):663-7. doi: 10.1007/s11695-011-0371-8.

Laparoscopic sleeve gastrectomy with duodenojejunal bypass for the treatment of type 2 diabetes in non-obese patients: technique and preliminary results.

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  • 1Department of Surgery, Faculty of Medicine, Hospital Universitario de Caracas, Universidad Central de Venezuela, Caracas, Venezuela, navarretesalvador@yahoo.com.

Abstract

BACKGROUND:

Medical treatment of type 2 diabetes has often insufficient clinical results at long term. Although the surgical option is a well-established alternative for obese patients, the procedures in non-obese are currently being developed.

METHODS:

A 12-month prospective trial with ten diabetic non-obese patients who underwent laparoscopic sleeve gastrectomy with duodenojejunal bypass is presented. Changes in fasting blood glucose, HbA1c, weight, and BMI were determined.

RESULTS:

There was a significant reduction in fasting glycemia and HbA1c at 1 year postoperative (p < 0.004). One patient had an intra-abdominal bleeding and a wound infection treated with blood transfusion and antibiotic therapy, respectively. The BMI decreased 12.1% and in any case it was reduced to less than 20 kg/m².

CONCLUSIONS:

Laparoscopic sleeve gastrectomy with duodenojejunal bypass is a promising procedure for the treatment of non-obese patients with type 2 diabetes. Studies with large number of patients and longer follow-up are necessary to make definitive conclusions.

PMID:
21336559
[PubMed - indexed for MEDLINE]
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