The enormous advances in genetics and genomics of the past decade have the potential to revolutionize health care, including mental health care, and bring about a system predominantly characterized by the practice of genomic and personalized medicine. This article briefly reviews the history of genetics and genomics and assesses the extent to which the results of genetic and genomic studies are currently being leveraged clinically for disease treatment and prevention. Relevant social, economic, and policy issues relevant to genomic medicine are also reviewed, and priority research areas in which further work is needed are identified.

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