Display Settings:

Format

Send to:

Choose Destination
We are sorry, but NCBI web applications do not support your browser and may not function properly. More information
    Comput Math Methods Med. 2011;2011:452320. doi: 10.1155/2011/452320. Epub 2010 Dec 30.

    Numerical solutions for a model of tissue invasion and migration of tumour cells.

    Source

    Department of Mathematics and Computer Science, University of Warmia and Mazury, Zolnierska 14, 10-561 Olsztyn, Poland.

    Abstract

    The goal of this paper is to construct a new algorithm for the numerical simulations of the evolution of tumour invasion and metastasis. By means of mathematical model equations and their numerical solutions we investigate how cancer cells can produce and secrete matrix degradative enzymes, degrade extracellular matrix, and invade due to diffusion and haptotactic migration. For the numerical simulations of the interactions between the tumour cells and the surrounding tissue, we apply numerical approximations, which are spectrally accurate and based on small amounts of grid-points. Our numerical experiments illustrate the metastatic ability of tumour cells.

    PMID:
    21331265
    [PubMed - indexed for MEDLINE]
    PMCID:
    PMC3017898
    Free PMC Article

    Images from this publication.See all images (15)Free text

    Figure 1
    Figure 3
    Figure 5
    Figure 7
    Figure 9
    Figure 11
    Figure 13
    Figure 15
    Figure 2
    Figure 4
    Figure 6
    Figure 8
    Figure 10
    Figure 12
    Figure 14

      Supplemental Content

      Icon for Hindawi Publishing Corporation Icon for PubMed Central

      Save items

      Recent activity

      Your browsing activity is empty.

      Activity recording is turned off.

      Turn recording back on

      See more...
      Write to the Help Desk