The role of plastic surgery in sarcoma treatment

Clin Transl Oncol. 2011 Feb;13(2):102-8. doi: 10.1007/s12094-011-0626-9.

Abstract

Introduction: Sarcomas are low-incidence tumours, but their poor prognosis and complex treatment require the work of a multidisciplinary medical team. The Plastic Surgery Service forms part of the Sarcoma Functional Unit in our centre, performing tumour exeresis as well as immediate reconstruction.

Materials and methods: We present a retrospective study on the experience of the Plastic Surgery Service of the Hospital Universitario de Bellvitge in the treatment of 133 sarcomas over 20 years.

Results: The surgical treatment was based on local radical surgery supported by primary reconstructive surgery in 42.9% of the cases, with an amputation rate in limb sarcomas of 9.7%. Radiotherapy and chemotherapy were used in the high-grade sarcomas as adjuvant treatment. The anatomical location of the head and neck was associated with the need for reconstructive procedures. Survival free from local recurrence was 84.72% at 5 years. Disease-specific survival was 81.22% at 5 years. The only prognostic factor for survival in our series was histological grade.

Conclusions: Primary reconstructive surgery has a fundamental role in sarcoma treatment enabling radical surgical resection, avoiding amputations and facilitating adjuvant treatments.

Publication types

  • Evaluation Study

MeSH terms

  • Adult
  • Aged
  • Combined Modality Therapy
  • Extremities / pathology
  • Extremities / surgery
  • Female
  • Humans
  • Male
  • Middle Aged
  • Neoplasm Recurrence, Local / surgery
  • Plastic Surgery Procedures / methods
  • Plastic Surgery Procedures / statistics & numerical data
  • Retrospective Studies
  • Salvage Therapy
  • Sarcoma / mortality
  • Sarcoma / pathology
  • Sarcoma / surgery*
  • Sarcoma / therapy
  • Soft Tissue Neoplasms / mortality
  • Soft Tissue Neoplasms / pathology
  • Soft Tissue Neoplasms / surgery*
  • Soft Tissue Neoplasms / therapy
  • Surgery, Plastic / methods
  • Surgery, Plastic / statistics & numerical data*
  • Survival Analysis