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Acta Otolaryngol. 2011 Mar;131(3):263-8. doi: 10.3109/00016489.2010.532155.

Blockage of longitudinal flow in Meniere's disease: A human temporal bone study.

Author information

  • 1Department of Otolaryngology, Tokyo Medical University, Japan.

Abstract

CONCLUSION:

Blockage of the endolymphatic duct is a significant finding in Meniere's disease. The position of the utriculo-endolymphatic valve (UEV) and blockage of the ductus reuniens in the temporal bones were not found to be directly indicative of Meniere's disease.

OBJECTIVE:

Comparison of blockage of the longitudinal flow of endolymph between ears affected by Meniere's disease and normal ears.

METHODS:

We examined 21 temporal bones from 13 subjects who had Meniere's disease and 21 normal temporal bones from 12 controls.

RESULTS:

The endolymphatic duct was blocked in five (23%) ears affected by Meniere's disease (p = 0.016). The utricular duct was blocked in 16 (76%) ears affected by Meniere's disease and 11 (52%) normal ears (p = 0.112). The saccular duct was blocked in 6 (28%) of ears affected by Meniere's disease and 16 (76%) normal ears (p = 0.001). The ductus reuniens was blocked in 10 (47%) ears affected by Meniere's disease and 10 (47%) normal ears (p = 1.000).

PMID:
21319945
[PubMed - indexed for MEDLINE]
PMCID:
PMC3055713
Free PMC Article

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