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Acta Otolaryngol. 2011 Mar;131(3):263-8. doi: 10.3109/00016489.2010.532155.

Blockage of longitudinal flow in Meniere's disease: A human temporal bone study.

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  • 1Department of Otolaryngology, Tokyo Medical University, Japan.



Blockage of the endolymphatic duct is a significant finding in Meniere's disease. The position of the utriculo-endolymphatic valve (UEV) and blockage of the ductus reuniens in the temporal bones were not found to be directly indicative of Meniere's disease.


Comparison of blockage of the longitudinal flow of endolymph between ears affected by Meniere's disease and normal ears.


We examined 21 temporal bones from 13 subjects who had Meniere's disease and 21 normal temporal bones from 12 controls.


The endolymphatic duct was blocked in five (23%) ears affected by Meniere's disease (p = 0.016). The utricular duct was blocked in 16 (76%) ears affected by Meniere's disease and 11 (52%) normal ears (p = 0.112). The saccular duct was blocked in 6 (28%) of ears affected by Meniere's disease and 16 (76%) normal ears (p = 0.001). The ductus reuniens was blocked in 10 (47%) ears affected by Meniere's disease and 10 (47%) normal ears (p = 1.000).

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