Discovery of TAK-733, a potent and sele... [Bioorg Med Chem Lett. 2011] - PubMed

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Structures reported by this article

Crystal Structure Of The Human Mitogen-Activated Protein Kinase Kinase 1 (Mek 1) In Complex With Ligand And Mgatp

PDB: 3PP1

Source: Homo sapiens

Method: X-Ray Diffraction

Resolution: 2.7 Å

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Discovery of TAK-733, a potent and selective MEK allosteric site inhibitor for t...
Discovery of TAK-733, a potent and selective MEK allosteric site inhibitor for the treatment of cancer.
Bioorg Med Chem Lett. 2011 Mar 1 ;21(5):1315-9. doi: 10.1016/j.bmcl.2011.01.071. Epub 2011 Jan 22 .

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