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Eur Child Adolesc Psychiatry. 2011 Feb;20(2):61-6. doi: 10.1007/s00787-010-0150-4. Epub 2011 Feb 5.

Irritability in children and adolescents: a challenge for DSM-5.

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  • 1King's College London Institute of Psychiatry, Box P085, De Crespigny Park, Denmark Hill, London SE5 8AF, UK.


Irritability has recently become a major focus of interest for clinicians and nosologists alike, and its position in the upcoming DSM-5 is currently debated. However, research on irritability has only recently started emerging. Here, I review the recent findings on irritability and its differentially strong relationship to depressive and generalised anxiety disorders compared to disruptive behaviours. Furthermore, I examine the importance of irritability in the recent debate about bipolar disorder in children and adolescents and discuss findings from research into severe mood dysregulation. I next address the relevance of irritability to the two core aims of developmental sensitivity and dimensionality. Finally, I critically discuss the recently proposed putative DSM-5 category of temper dysregulation disorder with dysphoria and make suggestions about future research directions.

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