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[Gene cloning of human dopaminergic D3 receptor and identification of its chromosome]
[Article in French]
Unité de Neurobiologie et Pharmacologie (U.n. 109) de l'I.N.S.E.R.M., Centre Paul-Broca, Paris.
The coding region of the human dopaminergic D3 receptor gene was cloned and sequenced. The deduced amino acid sequence displays a global homology of 78% with rat D3 receptor with a deletion of 46 residues within the third intracytoplasmic loop. Southern analysis assigned the human gene to chromosome 3.
PMID: 2129115 [PubMed - indexed for MEDLINE]
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Cited by 6 PubMed Central articles
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In vitro pharmacological profile of YM-43611, a novel D2-like receptor antagonist with high affinity and selectivity for dopamine D3 and D4 receptors.
Hidaka K, Tada S, Matsumoto M, Ohmori J, Tasaki Y, Nomura T, Usuda S, Yamaguchi T.
Br J Pharmacol. 1996 Apr; 117(8):1625-32.
[Br J Pharmacol. 1996]
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Selective loss of dopamine D3-type receptor mRNA expression in parietal and motor cortices of patients with chronic schizophrenia.
Schmauss C, Haroutunian V, Davis KL, Davidson M.
Proc Natl Acad Sci U S A. 1993 Oct 1; 90(19):8942-6.
[Proc Natl Acad Sci U S A. 1993]
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Linkage analysis of schizophrenia with five dopamine receptor genes in nine pedigrees.
Coon H, Byerley W, Holik J, Hoff M, Myles-Worsley M, Lannfelt L, Sokoloff P, Schwartz JC, Waldo M, Freedman R.
Am J Hum Genet. 1993 Feb; 52(2):327-34.
[Am J Hum Genet. 1993]
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