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Minerva Cardioangiol. 2011 Feb;59(1):101-8.

Iloprost in the management of peripheral arterial disease in patients with diabetes mellitus.

Author information

  • 1Sezione Piede Diabetico, Unità Operativa Malattie del Metabolismo e Diabetologia, Azienda Ospedaliero-Universitaria Pisana, Pisa, Italia. piaggesi@immr.med.unipi.it

Abstract

Diabetic complications in the lower extremities, especially those secondary to diabetic macroangiopathy, have increasingly become a clinical emergency, given the high prevalence and progression of the disease. Until recently, the only approach to treating advanced stage disease was medical therapy and major amputation; however, the advent of revascularization procedures has radically improved the prognosis of patients with critical lower limb ischemia. In this setting, iloprost holds a dual position: as first-choice therapy in patients ineligible for revascularization and as complementary therapy in candidates for surgical or endovascular revascularization.

PMID:
21285935
[PubMed - indexed for MEDLINE]
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