Format

Send to:

Choose Destination
See comment in PubMed Commons below
F1000 Biol Rep. 2010 Nov 24;2:83. doi: 10.3410/B2-83.

Creating transplant tolerance by taming adverse intragraft innate immunity.

Author information

  • 1Departments of Medicine and Surgery, Transplant Institute, Beth Israel Deaconess Medical Center, Harvard Medical School, 330 Brookline Avenue, E/CLS 608 Boston, MA 02215 USA.

Abstract

Certain forms of inflammation of an allograft are highly detrimental to the induction and maintenance of transplant tolerance as they foster stable commitment to graft-destructive, not graft-protective, forms of T-cell immunity. Hence, a reduction in adverse tissue inflammation may prove crucial in facilitating the induction and maintenance of a long-lasting state of transplant tolerance.

PMID:
21283601
[PubMed]
PMCID:
PMC3026643
Free PMC Article
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for PubMed Central
    Loading ...
    Write to the Help Desk