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Diabetes Care. 2011 Mar;34(3):646-8. doi: 10.2337/dc10-1754. Epub 2011 Jan 27.

Associations between concentrations of vitamin D and concentrations of insulin, glucose, and HbA1c among adolescents in the United States.

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  • 1Division of Adult and Community Health, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, Georgia, USA. eford@cdc.gov

Abstract

OBJECTIVE:

Our objective was to examine the associations between concentrations of vitamin D and concentrations of insulin, glucose, and HbA(1c) in a nationally representative sample of adolescents in the U.S.

RESEARCH DESIGN AND METHODS:

We used data for 1,941 adolescents, aged 12-17 years, who participated in the National Health and Nutrition Examination Survey between 2001 and 2006.

RESULTS:

Adjusted concentrations of insulin were ~24% lower among male subjects with a concentration of vitamin D ≥ 75 nmol/L than among male subjects with a concentration of vitamin D <50 nmol/L (P = 0.003). Concentrations of vitamin D were inversely associated with concentrations of glucose only among Mexican American male subjects (P = 0.007). No significant associations between concentrations of vitamin D and HbA(1c) were detected.

CONCLUSIONS:

Our results support an inverse association between concentrations of vitamin D and insulin primarily in adolescent male subjects.

PMID:
21273498
[PubMed - indexed for MEDLINE]
PMCID:
PMC3041198
Free PMC Article
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