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Pharmacy Department, Third Affiliated Hospital of Guangzhou Medical University, Guangzhou 510150, China.
Neurological complications associated with HIV-1 are being recognized as a common disorder in AIDS patients, especially patients with HIV-associated dementia (HAD). However, our knowledge of the complicated pathogenesis and clinical symptoms of HAD is limited by an incomplete understanding of the biology of HIV-1 in the nervous system. Therefore, this review focuses on the pathogenesis of HAD in the context of novel highly active antiretroviral therapy (HARRT) regimens.
Copyright © 2011 Institut Pasteur. Published by Elsevier SAS. All rights reserved.
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