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Microbes Infect. 2011 May;13(5):419-25. doi: 10.1016/j.micinf.2011.01.004. Epub 2011 Jan 22.

HIV-associated dementia in the era of highly active antiretroviral therapy (HAART).

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  • 1Pharmacy Department, Third Affiliated Hospital of Guangzhou Medical University, Guangzhou 510150, China.


Neurological complications associated with HIV-1 are being recognized as a common disorder in AIDS patients, especially patients with HIV-associated dementia (HAD). However, our knowledge of the complicated pathogenesis and clinical symptoms of HAD is limited by an incomplete understanding of the biology of HIV-1 in the nervous system. Therefore, this review focuses on the pathogenesis of HAD in the context of novel highly active antiretroviral therapy (HARRT) regimens.

Copyright © 2011 Institut Pasteur. Published by Elsevier SAS. All rights reserved.

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