Format

Send to:

Choose Destination
See comment in PubMed Commons below
Open Cardiovasc Med J. 2010 Nov 26;4:231-9. doi: 10.2174/1874192401004010231.

Animal models of cardiac disease and stem cell therapy.

Author information

  • 1Key Laboratory of Bioactive Materials, Ministry of Education, College of Life Science, Nankai University, Tianjin, China.

Abstract

Animal models that mimic cardiovascular diseases are indispensable tools for understanding the mechanisms underlying the diseases at the cellular and molecular level. This review focuses on various methods in preclinical research to create small animal models of cardiac diseases, such as myocardial infarction, dilated cardiomyopathy, heart failure, myocarditis and cardiac hypertrophy, and the related stem cell treatment for these diseases.

KEYWORDS:

Animal model; cardiac hypertrophy; dilated cardiomyopathy; heart failure; myocardial infarction; myocarditis; stem cell.

PMID:
21258568
[PubMed]
PMCID:
PMC3024564
Free PMC Article
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for PubMed Central
    Loading ...
    Write to the Help Desk