Warning: The NCBI web site requires JavaScript to function. more...
Generate a file for use with external citation management software.
Selective targeting of activating and inhibitory Smads by distinct WWP2 ubiquitin ligase isoforms differentially modulates TGFβ signalling and EMT.
Soond SM, Chantry A.
Oncogene. 2011 May 26;30(21):2451-62. Epub 2011 Jan 24.
Related citations
Role of SARA (SMAD anchor for receptor activation) in maintenance of epithelial cell phenotype.
Runyan CE, Hayashida T, Hubchak S, Curley JF, Schnaper HW.
J Biol Chem. 2009 Sep 11;284(37):25181-9. Epub 2009 Jul 20.
Mesalazine negatively regulates CDC25A protein expression and promotes accumulation of colon cancer cells in S phase.
Stolfi C, Fina D, Caruso R, Caprioli F, Fantini MC, Rizzo A, Sarra M, Pallone F, Monteleone G.
Carcinogenesis. 2008 Jun;29(6):1258-66. Epub 2008 May 20.
Axin and GSK3- control Smad3 protein stability and modulate TGF- signaling.
Guo X, Ramirez A, Waddell DS, Li Z, Liu X, Wang XF.
Genes Dev. 2008 Jan 1;22(1):106-20.
Post-transcriptional regulation of Smad7 in the gut of patients with inflammatory bowel disease.
Monteleone G, Del Vecchio Blanco G, Monteleone I, Fina D, Caruso R, Gioia V, Ballerini S, Federici G, Bernardini S, Pallone F, MacDonald TT.
Gastroenterology. 2005 Nov;129(5):1420-9.
RING finger-dependent ubiquitination by PRAJA is dependent on TGF-beta and potentially defines the functional status of the tumor suppressor ELF.
Saha T, Vardhini D, Tang Y, Katuri V, Jogunoori W, Volpe EA, Haines D, Sidawy A, Zhou X, Gallicano I, Schlegel R, Mishra B, Mishra L.
Oncogene. 2006 Feb 2;25(5):693-705.
CHIP controls the sensitivity of transforming growth factor-beta signaling by modulating the basal level of Smad3 through ubiquitin-mediated degradation.
Xin H, Xu X, Li L, Ning H, Rong Y, Shang Y, Wang Y, Fu XY, Chang Z.
J Biol Chem. 2005 May 27;280(21):20842-50. Epub 2005 Mar 21.
NEDD4-2 (neural precursor cell expressed, developmentally down-regulated 4-2) negatively regulates TGF-beta (transforming growth factor-beta) signalling by inducing ubiquitin-mediated degradation of Smad2 and TGF-beta type I receptor.
Kuratomi G, Komuro A, Goto K, Shinozaki M, Miyazawa K, Miyazono K, Imamura T.
Biochem J. 2005 Mar 15;386(Pt 3):461-70.
Ligand-dependent degradation of Smad3 by a ubiquitin ligase complex of ROC1 and associated proteins.
Fukuchi M, Imamura T, Chiba T, Ebisawa T, Kawabata M, Tanaka K, Miyazono K.
Mol Biol Cell. 2001 May;12(5):1431-43.
Ubiquitin-dependent degradation of TGF-beta-activated smad2.
Lo RS, Massagué J.
Nat Cell Biol. 1999 Dec;1(8):472-8.
Filters: Manage Filters
Your browsing activity is empty.
Activity recording is turned off.
Turn recording back on