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Pharmacol Res. 2011 Jul;64(1):1-3. doi: 10.1016/j.phrs.2011.01.007. Epub 2011 Jan 19.

Antiretroviral drugs in HIV-infected children.


Availability of highly active antiretroviral therapy has dramatically increased survival rates and substantially modified the course of HIV infection, which has now become a chronic disease both in adults and in children. Treatment strategies in paediatric patients have to face with specific challenges associated with selection of a successful antiretroviral drug regimen, long-lasting maintenance of adherence to therapy, short and long-term drug-related toxicities and emerging of extensive drug resistance. This review shows an up-to-date picture of the ultimate advances of antiretroviral therapy in HIV-infected children.

Copyright © 2011 Elsevier Ltd. All rights reserved.

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