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Am J Obstet Gynecol. 2011 Mar;204(3):209.e1-7. doi: 10.1016/j.ajog.2010.10.897. Epub 2011 Jan 17.

Evaluation of a screening tool for bleeding disorders in a US multisite cohort of women with menorrhagia.

Author information

  • 1Division of Hematology, UMDNJ-Robert Wood Johnson Medical School, New Brunswick, NJ 08903, USA. philipp@umdnj.edu

Abstract

OBJECTIVE:

The purpose of this study was to determine the usefulness of a simple screening tool for bleeding disorders in a multisite population of women with menorrhagia.

STUDY DESIGN:

Women with menorrhagia between the ages of 18 and 50 years from 6 geographically diverse US centers underwent hemostatic testing for bleeding disorders, complete blood cell count, and ferritin. A questionnaire that contained all elements of the 8-question screening tool was administered. Sensitivity of the screening tool, a screening tool with a pictorial blood assessment chart (PBAC) score of >185, and a screening tool with serum ferritin were calculated for hemostatic disorders.

RESULTS:

Two hundred and seventeen women who were identified with a PBAC score of ≥100 participated in the study. The sensitivity of the screening tool was 89% for hemostatic defects, and sensitivity increased to 93% and 95% with a serum ferritin level of ≤20 ng/mL and a PBAC score of >185, respectively.

CONCLUSION:

This study confirms the usefulness of a short screening tool for the stratification of women with menorrhagia for hemostatic evaluation.

Copyright © 2011 Mosby, Inc. All rights reserved.

PMID:
21247551
[PubMed - indexed for MEDLINE]
PMCID:
PMC4598044
Free PMC Article
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