Transpl Infect Dis. 2011 Jun;13(3):312-7. doi: 10.1111/j.1399-3062.2010.00595.x. Epub 2011 Jan 16.

West Nile virus encephalitis acquired via liver transplantation and clinical response to intravenous immunoglobulin: case report and review of the literature.

Rhee C, Eaton EF, Concepcion W, Blackburn BG.

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Department of Internal Medicine, Stanford University School of Medicine, Palo Alto, California, USA.

Abstract

A patient developed West Nile virus (WNV) encephalitis 2 weeks after receiving a liver transplant and recovered fully, following treatment with intravenous immunoglobulin (IVIg). Laboratory testing documented transmission from the organ donor. Clinicians should be suspicious for organ-transmitted WNV in any post-transplant patient who develops fever and neurological symptoms. We review previous cases of organ-transmitted WNV, the use of IVIg for WNV encephalitis, and the issue of organ donor screening.

PMID:: 21235711; [PubMed - indexed for MEDLINE]

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Immunoglobulins, Intravenous

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