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Rare Tumors. 2010 Dec 31;2(4):e66.

Familial adenomatous polyposis with synchronous invasive colonic carcinomas and metastatic jejunal adenocarcinoma in a Nigerian male.

Osuagwu CC, Okafor OC, Ezeome ER, Uche CE, Ememonu C, Kesieme E.

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Department of Surgery, Imo State University Teaching Hospital, Orlu, Imo state, Nigeria.

Abstract

Familial adenomatous polyposis is rare. Three cases were previously reported in Nigeria. An intriguing feature of this case is an ulcerated jejunal carcinoma which was metastatic rather than synchronous carcinoma. This patient presented with partial large bowel obstruction and the pathological analysis revealed 4 invasive adenocarcinomas, 3 in the colon and 1 in the jejunum (Dukes stage D). Palliative pancolectomy and jejunal tumour resection with chemotherapy was offered to him. He died eight months after surgery from disease progression. The challenges of managing a hereditary cancer syndrome in a resource poor country are highlighted.

PMID:: 21234258; [PubMed]
PMCID:: PMC3019601

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