Send to:

Choose Destination
See comment in PubMed Commons below
Trends Cogn Sci. 1998 Aug 1;2(8):281-8.

The functional anatomy of word comprehension and production.

Author information

  • 1Wellcome Department of Cognitive Neurology, Institute of Neurology, Queen Square, London, UK WC1N 3BG.


This review describes the functional anatomy of word comprehension and production. Data from functional neuroimaging studies of normal subjects are used to determine the distributed set of brain regions that are engaged during particular language tasks and data from studies of patients with neurological damage are used to determine which of these regions are necessary for task performance. This combination of techniques indicates that the left inferior temporal and left posterior inferior parietal cortices are required for accessing semantic knowledge; the left posterior basal temporal lobe and the left frontal operculum are required for translating semantics into phonological output and the left anterior inferior parietal cortex is required for translating orthography to phonology. Further studies are required to establish the specific functions of the different regions and how these functions interact to provide our sophisticated language system.

PubMed Commons home

PubMed Commons

How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Elsevier Science
    Loading ...
    Write to the Help Desk