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Radiol Med. 2011 Apr;116(3):432-43. doi: 10.1007/s11547-011-0620-2. Epub 2011 Jan 12.

Videourodynamics in patients with neurogenic bladder due to multiple sclerosis: our experience.

[Article in English, Italian]

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  • 1Radiologia Diagnostica e Interventistica, Universit√† di Pisa, Pisa, Italy.



The aims of this study were to: (a) analyse the most frequent morphofunctional features of the lower urinary tract observed during videourodynamic examination in patients with neurogenic bladder due to multiple sclerosis; (b) investigate the role of the videourodynamic examination in the clinical management of these patients; and (c) demonstrate the relationship between morphological and functional variables.


We performed videourodynamic examinations in 75 patients affected by neurogenic bladder secondary to multiple sclerosis.


The introduction of pharmacological therapy, based on clinical and functional evaluation of the lower urinary tract, is correlated with satisfactory morphofunctional outcomes, reducing moderate-to-severe postvoid residual (PVR; p < 0.1) and compliance (p < 0.05) at the price of reduced bladder sensation. Clinical management of these patients based on morphological evaluation of the lower urinary tract decreased the occurrence of detrusor-sphincter dyssynergy (DSD) and detrusor overactivity incontinence at the following examination.


Our study confirmed a relationship between detrusor overactivity and hypertonic bladder, bladder diverticula, vesicoureteral reflux, between detrusor underactivity and PVR and between DSD and bladder diverticula. Our data show how the videourodynamic examination may improve evaluation and urological management of these patients.

[PubMed - indexed for MEDLINE]
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