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Rev Med Suisse. 2010 Nov 24;6(272):2233-6, 2238-9.

[New perspectives for respiratory rehabilitation in COPD].

[Article in French]

Author information

  • 1Service de pneumologie, CHUV, 1011 Lausanne.


COPD is associated with some skeletal muscle dysfunction which contributes to a poor exercise tolerance. This dysfunction results from multiple factors: physical inactivity, corticosteroids, smoking, malnutrition, anabolic deficiency, systemic inflammation, hypoxia, oxidative stress. Respiratory rehabilitation is based on exercise training and allows patients with COPD to experience less dyspnoea, and to improve their exercise tolerance and quality of life. Not all patients, however, benefit from rehabilitation. Acknowledging the different factors leading to muscular dysfunction allows one to foresee new avenues to improve efficacy of exercise training in COPD.

[PubMed - indexed for MEDLINE]
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