Top: Query summary page. Query summaries display one record (row) for each gene matching the query. One can query by gene symbols, by various gene IDs, and by genome coordinates. A query for two genes by gene symbol (Casp4, Lefty1) is shown. The gene column displays the official gene symbol, linked to the corresponding gene pages at MGI. Gene specific links to genome browsers and other external sites are provided. The ‘IKMC Knockout Attempts’ column lists all IKMC programs working on the gene. The status of the most advanced targeting effort per program is shown, with a link to more details. The availability of IKMC products is indicated by Order links to the respective IKMC repositories. The ‘Other Resources’ column displays the number of mutant ES cells and mice reported by the IMSR, IGTC, and MGI with links to the corresponding entries at these sites.
Bottom: Query details page. This page lists all the IKMC knockout attempts for a given gene. The most advanced projects are displayed first. Available products are indicated by Order links to the respective repositories. Clicking on the ‘Allele Details’ link (to the right of the project status bar) opens a graphical display illustrating the features of the mutant allele generated by the project. The ‘View this project’ link (red arrow) leads to more comprehensive targeting vector and mutant allele information.

Top left: Part of the page that shows the search results for ‘Angelman Syndrome’, upon using the ‘Human Disease (OMIM) Browser’ at MGI.
Top right: ‘Human Disease and Mouse Model Detail’ page for Angelman Syndrome. Based on available phenotypic data, orthologous mouse and human genes are categorized according to their association with human disease characteristics. Mouse models for the respective categories are listed at the bottom part of the page. Each mouse model record specifies the exact allele composition and the genetic background under which the phenotype was observed, and points to the corresponding publication. Each mouse model record links to much more detailed allele and phenotypic data (red arrow).
Bottom: ‘Allele Detail’ page for Ube3^tm1Alb. This page provides detailed molecular and phenotypic information for each allele. The sections ‘Phenotype summary’ and ‘Phenotypic data by genotype’ can be expanded by using the ‘show all’ functions or by clicking on the triangles.

Top left: Part of the ‘Access Data’ section of the Cre-Portal home page. A query for mouse lines that carry a recombinase under the Nes promoter is shown. Top right: Query results summary. The bottom section lists a record for each allele / mouse line that matches the query. The ‘Recombinase Data’ column indicates in how many anatomical systems recombinase activity has been measured. Clicking on the triangle expands the display to show the anatomical system analyzed. An alternative way to look up data for specific anatomical systems is to add corresponding data columns to the display by checking boxes in the top half of the page and then clicking the ‘Reset Page’ button.
Bottom: Detail Page showing the recombinase activity data for one allele, Tg(Nes-cre)1Kln, in one anatomical system, the alimentary system. Images can be enlarged by dragging their corners. Specific anatomical structures within the alimentary system in which activity was found are recorded, together with the assayed age, the level and patterns of activity in the specified anatomical structure, and references to figures and publications. Additional assay and genetic background information is accessible via specific tabs (bottom right section of display).