Display Settings:

Format

Send to:

Choose Destination
Rev Soc Bras Med Trop. 2010 Nov-Dec;43(6):682-5.

[Bacterial contamination on platelet concentrates: identification, antimicrobial susceptibility profile and transfusion-related sepsis].

[Article in Portuguese]

Author information

  • 1Universidade Federal de Santa Maria, Santa Maria, RS.

Abstract

INTRODUCTION:

Bacterial sepsis associated with the transfusion of platelet concentrates (PCs) results in serious clinical implications for patients. Given these implications, certain procedures have been integrated into the preparation and quality control of blood components to reduce the risk of bacterial contamination. This article describes the prevalence of bacterial contamination on transfused PCs, the bacterial spectrum detected and their antimicrobial susceptibility profile and transfusion reactions in receptors.

METHODS:

A total of 292 PCs (278 random and 14 per apheresis) from the Blood Center of the State of Rio Grande do Sul (HEMORGS), located in the city of Santa Maria, were tested. Quantities of 100 μL and 200 μL were collected from platelet bag tubing and seeded using two methodologies.

RESULTS:

Using the qualitative methodology, bacteria were isolated in five units (1.7%; 5/292), while only one was isolated using the quantitative methodology. Staphylococcus epidermidis was the microorganism identified in all samples. Two patients died of transfusion-related sepsis.

CONCLUSIONS:

Bacterial contamination due to PC transfusion is considered a major public health problem due to its association with high rates of morbidity and mortality. In this study only gram-positive microorganisms were isolated and none of the samples obtained by apheresis presented contamination.

PMID:
21181023
[PubMed - indexed for MEDLINE]
Free full text
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Scientific Electronic Library Online
    Loading ...
    Write to the Help Desk