Send to:

Choose Destination
See comment in PubMed Commons below
Clin Exp Immunol. 2011 Feb;163(2):131-46. doi: 10.1111/j.1365-2249.2010.04296.x. Epub 2010 Dec 22.

Clinical immunology review series: an approach to desensitization.

Author information

  • 1Department of Allergy and Immunology, Birmingham Heartlands Hospital, UK.


Allergen immunotherapy describes the treatment of allergic disease through administration of gradually increasing doses of allergen. This form of immune tolerance induction is now safer, more reliably efficacious and better understood than when it was first formally described in 1911. In this paper the authors aim to summarize the current state of the art in immunotherapy in the treatment of inhalant, venom and drug allergies, with specific reference to its practice in the United Kingdom. A practical approach has been taken, with reference to current evidence and guidelines, including illustrative protocols and vaccine schedules. A number of novel approaches and techniques are likely to change considerably the way in which we select and treat allergy patients in the coming decade, and these advances are previewed.

© 2010 The Authors. Clinical and Experimental Immunology © 2010 British Society for Immunology.

[PubMed - indexed for MEDLINE]
Free PMC Article
PubMed Commons home

PubMed Commons

How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Wiley Icon for PubMed Central
    Loading ...
    Write to the Help Desk