[Pandemic influenza vaccines. How should they be designed?]

Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz. 2010 Dec;53(12):1238-41. doi: 10.1007/s00103-010-1159-z.
[Article in German]

Abstract

Pandemic influenza vaccines have to fulfill specific requirements. In contrast to seasonal influenza vaccines, they have to be effective even in an immunologically naïve population. In addition, they should be available in a relatively short period of time and should be produced at an unprecedented speed in huge amounts. For this reason, they need a specific design which has to be different from that of seasonal vaccines. With the given technological possibilities, antigen-sparing adjuvanted vaccines most closely fulfill the requirements of an ideal pandemic vaccine.

Publication types

  • English Abstract

MeSH terms

  • Drug Design*
  • Germany / epidemiology
  • Humans
  • Influenza A Virus, H1N1 Subtype*
  • Influenza Vaccines / biosynthesis*
  • Influenza Vaccines / therapeutic use*
  • Influenza, Human / epidemiology
  • Influenza, Human / prevention & control*
  • Pandemics / prevention & control*
  • Pandemics / statistics & numerical data

Substances

  • Influenza Vaccines