Format

Send to:

Choose Destination
See comment in PubMed Commons below
Cytogenet Genome Res. 2011;133(2-4):202-8. doi: 10.1159/000321794. Epub 2010 Dec 8.

Meiotic studies of a 38,XY/39,XXY mosaic boar.

Author information

  • 1UMR 444 INRA-ENVT Génétique Cellulaire, Toulouse, France. a.pinton@envt.fr

Abstract

Klinefelter's syndrome (KS) is the most common sex chromosome abnormality identified in human males. This syndrome is generally associated with infertility. Men with KS may have a 47,XXY or a 46,XY/47,XXY karyotype. Studies carried out in humans and mice suggest that only XY cells are able to enter and complete meiosis. These cells could originate from the XY cells present in mosaic patients or from XXY cells that have lost one X chromosome. In pig, only 3 cases of pure 39,XXY have been reported until now, and no meiotic analysis was carried out. For the first time in pig species we report the analysis of a 38,XY/39,XXY boar and describe the origin of the supplementary X chromosome and the chromosomal constitutions of the germ and Sertoli cells.

Copyright © 2010 S. Karger AG, Basel.

PMID:
21150170
[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for S. Karger AG, Basel, Switzerland
    Loading ...
    Write to the Help Desk